This is a series of posts that are on basic surgical knowledge and surgical principles.
I have also included some weird and wonderful signs
Hamman’s sign: crepitus heard on auscultation of the heart beat in symphony with them indicating mediastinal air (heard following perforation of the body of the oesophagus).
Cowden’s PTEN 10q22.
GI Hamartomas, breast cancer, thyroid, cervix and uterus
Turners Syndrome X monosomy, absence of other X. Barr body.
Bicuspid aortic valve, coarctation aorta, webbed neck
Big testes, long narrow face, learning difficulties.
X linked. Presents in babies. Deficiency of phosphoribosyltrnasferase. Uric acid build up.
Plummer Vinson/Patterson brown kelly
Oesophageal web, fe def anaemia,
P53 sarcoma versar leukamia adrenal.
Absent pec major and breast.
Thrombosis of ax vein or subclavian
Right common iliac artery presses on left CIV causing thrombosis.
Impotence, buttock claudication, absent femorals.
Osler Weber Rendu (HHT)
Autosomal dominant. Telangectasia, bleeding.
Port wine, glaucoma, leptomeningeal angioma, mental retardation,
itz Hugh Curtis
PID usually chlmaydia causes perihepatic adhesions and pain
In a giant liver haemangioma, get sequestration of platelets and thrombocytopenia.
Hepatic vein thrombosis
Von Hippel Lindau
Clear cell renal ca, occular angiomas, pancreas, haemangioblastomas
VIPoma non beta islet cells of pancreas
Vomiting, crepitus, chest pain in Perf oesophagus
Fem pulse is decreased in presence of persistent sciatic artery.